MED12 Antikörper

Produktnummer ABIN5699865

Produktdetails anti-MED12 Antikörper

Target: MED12 (Mediator Complex Subunit 12 (MED12))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED12 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Immunogen: mediator complex subunit 12

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu MED12

Target: MED12 (Mediator Complex Subunit 12 (MED12))

Andere Bezeichnung: MED12 (MED12 Produkte)

Synonyme: ARC240 antikoerper, CAGH45 antikoerper, FGS1 antikoerper, HOPA antikoerper, MED12S antikoerper, OHDOX antikoerper, OKS antikoerper, OPA1 antikoerper, TNRC11 antikoerper, TRAP230 antikoerper, 230kDa antikoerper, Mopa antikoerper, OPA-1 antikoerper, Tnrc11 antikoerper, Trap230 antikoerper, mediator complex subunit 12 antikoerper, MED12 antikoerper, Med12 antikoerper, med12 antikoerper

Hintergrund: Synonyms:ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230 Background:Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway.

Molekulargewicht: 230 kDa

Gen-ID: 9968

UniProt: Q93074

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Tube Formation