ARL3 Antikörper

Produktnummer ABIN5699145

Produktdetails anti-ARL3 Antikörper

Target: ARL3 (ADP-Ribosylation Factor-Like 3 (ARL3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunogen: ADP-ribosylation factor-like 3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab00576(ARL3 antibody) at dilution of 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu ARL3

Target: ARL3 (ADP-Ribosylation Factor-Like 3 (ARL3))

Andere Bezeichnung: ARL3 (ARL3 Produkte)

Synonyme: ARFL3 antikoerper, si:ch211-208d15.4 antikoerper, wu:fj22g05 antikoerper, arfl3 antikoerper, arl3 antikoerper, ADP ribosylation factor like GTPase 3 antikoerper, ADP-ribosylation factor-like 3 antikoerper, ADP ribosylation factor like GTPase 3 S homeolog antikoerper, ADP-ribosylation factor-like protein 3 antikoerper, ARL3 antikoerper, arl3 antikoerper, Arl3 antikoerper, arl3.1.S antikoerper, arl-3 antikoerper

Hintergrund: Synonyms:ARFL3 Background:Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors(GEF) and GTPase-activating proteins(GAP). Required for normal cytokinesis and cilia signaling. Requires assistance from GTPase-activating proteins(GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for targeting proteins such as NPHP3 to the ciliary membrane by releasing myristoylated NPHP3 from UNC119B cargo adapter into the cilium. Does not act as an allosteric activator of the cholera toxin catalytic subunit.

Molekulargewicht: 20 kDa

Gen-ID: 403

UniProt: P36405