TSHZ3 Antikörper

Produktnummer ABIN5698742

Produktdetails anti-TSHZ3 Antikörper

Target: TSHZ3 (ZNF537) (Zinc Finger Protein 537 (ZNF537))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TSHZ3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Immunogen: teashirt zinc finger homeobox 3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB : 1:200-1:2000

Kommentare:

mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab09046( TSHZ3 Antibody) at dilution of 1:600

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu TSHZ3

Target: TSHZ3 (ZNF537) (Zinc Finger Protein 537 (ZNF537))

Andere Bezeichnung: TSHZ3 (ZNF537 Produkte)

Synonyme: ZNF537 antikoerper, A630038G13Rik antikoerper, Tsh3 antikoerper, Zfp537 antikoerper, mKIAA1474 antikoerper, teashirt3 antikoerper, TSH3 antikoerper, teashirt zinc finger homeobox 3 antikoerper, teashirt zinc finger family member 3 antikoerper, TSHZ3 antikoerper, Tshz3 antikoerper

Hintergrund: Synonyms:FLJ54422, KIAA1474, Teashirt homolog 3, TSH3, TSHZ3, Zinc finger protein 537, ZNF537 Background:Transcriptional regulator involved in developmental processes. Function in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s). Regulates the development of neurons involved in both respiratory rhythm and airflow control. Promotes maintenance of nucleus ambiguus(nA) motoneurons, which govern upper airway function, and establishes a respiratory rhythm generator(RRG) activity compatible with survival at birth. Involved in the differentiation of the proximal uretic smooth muscle cells during developmental processes. Involved in the up-regulation of myocardin, that directs the expression of smooth muscle cells in the proximal ureter.

Molekulargewicht: 87kDa

Gen-ID: 57616

UniProt: Q63HK5

Pathways: Regulation of Muscle Cell Differentiation