SNX6 Antikörper
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- Target Alle SNX6 Antikörper anzeigen
- SNX6 (Sorting Nexin 6 (SNX6))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SNX6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Immunogen
- sorting nexin 6
- Isotyp
- IgG
- Top Product
- Discover our top product SNX6 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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RAW 264.7 cells were subjected to SDS PAGE followed by western blot with FNab08095( SNX6 Antibody) at dilution of 1:600
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- SNX6 (Sorting Nexin 6 (SNX6))
- Andere Bezeichnung
- SNX6 (SNX6 Produkte)
- Synonyme
- MGC75952 antikoerper, MGC80251 antikoerper, im:7146294 antikoerper, wu:fa55b10 antikoerper, zgc:110798 antikoerper, MSTP010 antikoerper, TFAF2 antikoerper, 2010006G21Rik antikoerper, 2610032J07Rik antikoerper, 2810425K19Rik antikoerper, AU018928 antikoerper, C85963 antikoerper, sorting nexin 6 antikoerper, sorting nexin 6 L homeolog antikoerper, snx6 antikoerper, snx6.L antikoerper, SNX6 antikoerper, Snx6 antikoerper
- Hintergrund
- Synonyms: Background:Involved in several stages of intracellular trafficking. Interacts with membranes phosphatidylinositol 3,4-bisphosphate and/or phosphatidylinositol 4,5-bisphosphate(Probable). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex(PubMed:19935774). The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network(TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier(ETC)(Probable). Does not have in vitro vesicle-to-membrane remodeling activity(PubMed:23085988). Involved in retrograde endosome-to-TGN transport of lysosomal enzyme receptor IGF2R(PubMed:17148574). May function as link between transport vesicles and dynactin(Probable). Negatively regulates retrograde transport of BACE1 from the cell surface to the trans-Golgi network(PubMed:20354142). Involved in E-cadherin sorting and degradation, inhibits PIP5K1C isoform 3-mediated E-cadherin degradation(PubMed:24610942). In association with GIT1 involved in EGFR degradation. Promotes lysosomal degradation of CDKN1B(By similarity). May contribute to transcription regulation(Probable).
- Gen-ID
- 58533
- UniProt
- Q9UNH7
- Pathways
- EGFR Signaling Pathway
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