Prosaposin Antikörper
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- Target Alle Prosaposin (PSAP) Antikörper anzeigen
- Prosaposin (PSAP)
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Prosaposin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Immunogen
- prosaposin
- Isotyp
- IgG
- Top Product
- Discover our top product PSAP Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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HepG2 cells were subjected to SDS PAGE followed by western blot with FNab06843( PSAP Antibody) at dilution of 1:600
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- Prosaposin (PSAP)
- Andere Bezeichnung
- PSAP (PSAP Produkte)
- Synonyme
- GLBA antikoerper, SAP1 antikoerper, AI037048 antikoerper, SGP-1 antikoerper, SGP1A antikoerper, cb759 antikoerper, wu:fa14a06 antikoerper, wu:fb36e02 antikoerper, wu:fb58g07 antikoerper, PSAP antikoerper, PSP-A antikoerper, SFTPA1B antikoerper, SP-A antikoerper, prosaposin antikoerper, surfactant protein A1 antikoerper, PSAP antikoerper, Psap antikoerper, psap antikoerper, LOC100011417 antikoerper, LOC100304726 antikoerper, LOC100526719 antikoerper, SFTPA1 antikoerper
- Hintergrund
- Synonyms:GLBA, SAP1 Background:Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase(EC 3.2.1.45) and galactosylceramide by beta-galactosylceramidase(EC 3.2.1.46). Saposin-C apparently acts by combining with the enzyme and acidic lipid to form an activated complex, rather than by solubilizing the substrate. Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A(EC 3.1.6.8), GM1 gangliosides by beta-galactosidase(EC 3.2.1.23) and globotriaosylceramide by alpha-galactosidase A(EC 3.2.1.22). Saposin-B forms a solubilizing complex with the substrates of the sphingolipid hydrolases. Saposin-D is a specific sphingomyelin phosphodiesterase activator(EC 3.1.4.12). Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling. Saposins are specific low-molecular mass non-enzymic proteins, they participate in the lysosomal degradation of sphingolipids, which takes place by the sequential action of specific hydrolases.
- Gen-ID
- 5660
- UniProt
- P07602
- Pathways
- Positive Regulation of Endopeptidase Activity
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