MBD3 Antikörper

Produktnummer ABIN5698132

Produktdetails anti-MBD3 Antikörper

Target: MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MBD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Immunogen: methyl-CpG binding domain protein 3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Y79 cells were subjected to SDS PAGE followed by western blot with FNab05035(MBD3 antibody) at dilution of 1:600

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu MBD3

Target: MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))

Andere Bezeichnung: MBD3 (MBD3 Produkte)

Synonyme: xmbd3 antikoerper, MGC69548 antikoerper, MBD3 antikoerper, DKFZp459N1635 antikoerper, AI181826 antikoerper, AU019209 antikoerper, methyl-CpG binding domain protein 3 S homeolog antikoerper, methyl-CpG binding domain protein 3 antikoerper, mbd3.S antikoerper, mbd3 antikoerper, MBD3 antikoerper, Mbd3 antikoerper

Hintergrund: Synonyms: Background:Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself(PubMed:12124384). Binds to DNA with a preference for sites containing methylated CpG dinucleotides(in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides(PubMed:24307175). Recruits histone deacetylases and DNA methyltransferases.

Molekulargewicht: 33 kDa

Gen-ID: 53615

UniProt: O95983

Pathways: Chromatin Binding