TNPO2 Antikörper

Produktnummer ABIN5698048

Produktdetails anti-TNPO2 Antikörper

Target: TNPO2 (Transportin 2 (TNPO2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNPO2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Immunogen: transportin 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu TNPO2

Target: TNPO2 (Transportin 2 (TNPO2))

Andere Bezeichnung: TNPO2 (TNPO2 Produkte)

Synonyme: TNPO2 antikoerper, IPO3 antikoerper, KPNB2B antikoerper, TRN2 antikoerper, ik:tdsubc_2a7 antikoerper, tdsubc_2a7 antikoerper, wu:fb01c02 antikoerper, wu:fe01f03 antikoerper, wu:fe16e12 antikoerper, xx:tdsubc_2a7 antikoerper, zgc:101009 antikoerper, 1110034O24Rik antikoerper, AA414969 antikoerper, AI464345 antikoerper, AI852433 antikoerper, Knpb2b antikoerper, Kpnb2b antikoerper, transportin 2 antikoerper, transportin 2 L homeolog antikoerper, transportin 2 (importin 3, karyopherin beta 2b) antikoerper, TNPO2 antikoerper, tnpo2.L antikoerper, Tnpo2 antikoerper, tnpo2 antikoerper

Hintergrund: Synonyms: Background:Probably functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals(NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex(NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus(By similarity).

Gen-ID: 30000

UniProt: O14787