GPR161 Antikörper

Produktnummer ABIN5697750

Produktdetails anti-GPR161 Antikörper

Target: GPR161 (G Protein-Coupled Receptor 161 (GPR161))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPR161 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogen: G protein-coupled receptor 161

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab03598(GPR161 antibody) at dilution of 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu GPR161

Target: GPR161 (G Protein-Coupled Receptor 161 (GPR161))

Andere Bezeichnung: GPR161 (GPR161 Produkte)

Synonyme: RE2 antikoerper, Gm208 antikoerper, Gm208Gpr antikoerper, vl antikoerper, RGD1563245 antikoerper, si:bz20i5.4 antikoerper, si:rp71-20i5.4 antikoerper, G protein-coupled receptor 161 antikoerper, GPR161 antikoerper, Gpr161 antikoerper, gpr161 antikoerper

Hintergrund: Synonyms: Background:Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown(By similarity).

Molekulargewicht: 70 kDa

Gen-ID: 23432

UniProt: Q8N6U8

Pathways: cAMP Metabolic Process