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alpha Actinin 4 Antikörper

ACTN4 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IP, FACS, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5696883
  • Target Alle alpha Actinin 4 (ACTN4) Antikörper anzeigen
    alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
    Reaktivität
    • 85
    • 44
    • 41
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 78
    • 7
    Kaninchen
    Klonalität
    • 67
    • 17
    Polyklonal
    Konjugat
    • 53
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser alpha Actinin 4 Antikörper ist unkonjugiert
    Applikation
    • 66
    • 30
    • 26
    • 17
    • 16
    • 14
    • 13
    • 12
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunofluorescence (IF)
    Immunogen
    actinin, alpha 4
    Isotyp
    IgG
    Top Product
    Discover our top product ACTN4 Primärantikörper
  • Applikationshinweise
    WB :1:500-1:5000,IHC:1:20-1:200,IP:1:500-1:5000,IF:1:10-1:100
    Kommentare

    HepG2 cells were subjected to SDS PAGE followed by western blot with FNab00123(ACTN4 antibody) at dilution of 1:500

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze / thaw cycles.
    Lagerung
    -20 °C
    Haltbarkeit
    12 months
  • Target
    alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
    Andere Bezeichnung
    ACTN4 (ACTN4 Produkte)
    Synonyme
    fsgs antikoerper, fsgs1 antikoerper, C77391 antikoerper, ACTININ-4 antikoerper, FSGS antikoerper, FSGS1 antikoerper, wu:fb53f05 antikoerper, zgc:63508 antikoerper, actinin alpha 4 antikoerper, actinin, alpha 4 antikoerper, actinin alpha 4 S homeolog antikoerper, actn4 antikoerper, ACTN4 antikoerper, Actn4 antikoerper, actn4.S antikoerper
    Hintergrund
    Synonyms:ACTININ 4, actinin, alpha 4, ACTN4, Alpha actinin 4, DKFZp686K23158, F actin cross linking protein, FSGS, FSGS1, Non muscle alpha actinin 4 Background:F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein(Probable). Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation(PubMed:15772161). Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions(By similarity). May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA(PubMed:22351778).
    Molekulargewicht
    105kDa
    Gen-ID
    81
    UniProt
    O43707
    Pathways
    Proton Transport
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