ALDH5A1 Antikörper (Internal Region)

Produktnummer ABIN569594

Produktdetails anti-ALDH5A1 Antikörper

Target: ALDH5A1 (Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1))

Bindungsspezifität: AA 485-496, Internal Region

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser ALDH5A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequenz: C-SQDPAQIWRV AE

Spezifität: This antibody is expected to recognize both reported isoforms (NP_733936.1, NP_001071.1).

Kreuzreaktivität (Details): Species reactivity (expected):Bovine.
Species reactivity (tested):Human, Mouse, Rat.

Aufreinigung: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of Human ALDH5A1.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ALDH5A1

Target: ALDH5A1 (Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1))

Andere Bezeichnung: ALDH5A1 / SSADH (ALDH5A1 Produkte)

Synonyme: SSADH antikoerper, SSDH antikoerper, Ssadh antikoerper, 6330403E24Rik antikoerper, Ahd-1 antikoerper, Ahd1 antikoerper, D630032B01Rik antikoerper, OTTMUSG00000000613 antikoerper, Ssdh1 antikoerper, aldehyde dehydrogenase 5 family member A1 antikoerper, aldehyde dehydrogenase 5 family, member A1 antikoerper, aldhehyde dehydrogenase family 5, subfamily A1 antikoerper, ALDH5A1 antikoerper, aldh5a1 antikoerper, Aldh5a1 antikoerper

Hintergrund: Defects in ALDH5A1 are the cause of succinate semialdehyde dehydrogenase deficiency (SSADH deficiency) [MIM:271980]. SSADH deficiency is a rare inborn error in the metabolism of 4-aminobutyric acid (GABA) which leads to accumulation of 4-hydroxybutyric acid in physiologic fluids of patients. The disease is characterized by severe ataxia and by mildly retarded psychomotor development.Synonyms: Aldehyde dehydrogenase family 5 member A1, NAD(+)-dependent succinic semialdehyde dehydrogenase, Succinate-semialdehyde dehydrogenase, mitochondrial

Molekulargewicht: 58.7kDa (NP_733936.1).

Gen-ID: 7915

NCBI Accession: NP_001071

UniProt: P51649

Pathways: Monocarboxylic Acid Catabolic Process