POU2F1 Antikörper (Internal Region)

Produktnummer ABIN569583

Produktdetails anti-POU2F1 Antikörper

Target: POU2F1 (POU Domain, Class 2, Transcription Factor 1 (POU2F1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte, Schwein, Hund, Rind (Kuh)

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser POU2F1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: C-NVQSKSNEES GDSQQ

Spezifität: Recognizes POU2F1 / OCT1

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Canine (Dog), Bovine, Pig.
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Synthetic peptide corresponding to the internal region (near N Terminus) of Human POU2F1 (NP_002688.2). Genename: POU2F1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu POU2F1

Target: POU2F1 (POU Domain, Class 2, Transcription Factor 1 (POU2F1))

Andere Bezeichnung: POU2F1 / OCT1 (POU2F1 Produkte)

Synonyme: OCT1 antikoerper, OTF1 antikoerper, oct-1B antikoerper, POU2F1 antikoerper, 2810482H01Rik antikoerper, NF-A1 antikoerper, Oct-1 antikoerper, Oct1 antikoerper, Otf-1 antikoerper, Otf1 antikoerper, chOCT-1 antikoerper, oct-1 antikoerper, oct1 antikoerper, pou2f1r antikoerper, fc07d06 antikoerper, wu:fc07d06 antikoerper, zgc:158360 antikoerper, POU class 2 homeobox 1 antikoerper, POU domain, class 2, transcription factor 1 antikoerper, POU class 2 homeobox 1 S homeolog antikoerper, POU class 2 homeobox 1b antikoerper, POU2F1 antikoerper, Pou2f1 antikoerper, pou2f1.S antikoerper, pou2f1b antikoerper

Hintergrund: Octamer transcrIPPtional factor 1 (Oct-1) is a 90 kDa transcrIPPtion factor that binds to the octamer motif ATTTGCAT. This ubiquitous regulatory element is most conspicuous in B cells, where it is found in every immunoglobulin (Ig) promoter and in most Ig enhancers. In addition, Oct-1 binding also activates the promoters of the genes for some small nuclear RNAs (snRNA) and for histone H2B. Oct-1 protein is expressed in multIPPle tissues although some Oct-1 isoforms appear to be tissue specific and the homologous Oct-2 appears to be restricted in expression to B-cells. At least in B-cells, the Oct proteins bind to DNA together with another protein transcrIPPtion factor, octamer binding factor-1 (OBF-1), to form a ternary complex.Synonyms: NF-A1, OTF1, Oct-1, Octamer-binding protein 1, Octamer-binding transcription factor 1, Otf-1, POU domain class 2 transcription factor 1

Gen-ID: 5451

NCBI Accession: NP_002688

UniProt: P14859