Periaxin Antikörper (AA 1-91) (DyLight 488)

Produktnummer ABIN7354670

Produktdetails anti-Periaxin Antikörper (DyLight 488)

Target: Periaxin (PRX)

Bindungsspezifität: AA 1-91

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Periaxin Antikörper ist konjugiert mit DyLight 488

Applikation: Flow Cytometry (FACS)

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG Polyclonal Anti-Human PRX Antibody DyLight® 488 Conjugated, Flow Validated.

Immunogen: E. coli-derived human PRX recombinant protein (Position: M1-K91).

Anwendungsinformationen

Applikationshinweise:

Application Details: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: At 2-8°C for one year. Protect from light. Do not freeze.

Details zu Periaxin

Target: Periaxin (PRX)

Andere Bezeichnung: PRX (PRX Produkte)

Synonyme: xprx antikoerper, MGC89167 antikoerper, CMT4F antikoerper, L-Periaxin antikoerper, periaxin antikoerper, prx antikoerper, PRX antikoerper, Prx antikoerper

Hintergrund:

Synonyms: Periaxin, PRX, KIAA1620

Tissue Specificity: Detected in spinal cord (PubMed:11133365). Isoform 1 and isoform 2 are found in sciatic nerve and Schwann cells (PubMed:11157804).

Background: Periaxin is a protein that in humans is encoded by the PRX gene. This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein). Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy.