SCRIB Antikörper (AA 172-409)

Produktnummer ABIN5693286

Produktdetails anti-SCRIB Antikörper

Target: SCRIB (Scribbled Homolog (SCRIB))

Bindungsspezifität: AA 172-409

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCRIB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Marke: Picoband™

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for SCRIBBLE detection. Tested with WB, IHC-F, ICC, FCM, Direct ELISA in Human,Mouse,Rat.

Immunogen: E. coli-derived human SCRIBBLE recombinant protein (Position: F172-K409).

Anwendungsinformationen

Applikationshinweise:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(F) and ICC.

Application Details: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry(Frozen Section), 0.5-1 μg/mL
Immunocytochemistry, 0.5-1 μg/mL
Flow Cytometry, 1-3 μg/1x10⁶ cells
Direct ELISA, 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Details zu SCRIB

Target: SCRIB (Scribbled Homolog (SCRIB))

Andere Bezeichnung: SCRIB (SCRIB Produkte)

Synonyme: 0424/05 antikoerper, CG31082 antikoerper, CG42614 antikoerper, CG43398 antikoerper, CG5462 antikoerper, CG5467 antikoerper, CT17324 antikoerper, Dmel\\CG43398 antikoerper, Dmel_CG31082 antikoerper, Dmel_CG42614 antikoerper, Dmel_CG5462 antikoerper, Dmel_CG5467 antikoerper, MENE (3R)-F antikoerper, SCR antikoerper, Scb antikoerper, Scrb antikoerper, Scrib antikoerper, ird antikoerper, ird15 antikoerper, l(3)673 antikoerper, l(3)S042405 antikoerper, l(3)c00119 antikoerper, l(3)j7B3 antikoerper, scrb antikoerper, smi97B antikoerper, vart antikoerper, AI118201 antikoerper, CRIB antikoerper, Crc antikoerper, SCRIB1 antikoerper, Scrb1 antikoerper, mKIAA0147 antikoerper, vartul antikoerper, scrb1 antikoerper, scribble antikoerper, scribble1 antikoerper, si:ch211-12p8.1 antikoerper, si:zc12p8.1 antikoerper, CRIB1 antikoerper, SCRB1 antikoerper, Vartul antikoerper, scribbled antikoerper, scribbled planar cell polarity antikoerper, scribbled planar cell polarity protein antikoerper, scrib antikoerper, Scrib antikoerper, SCRIB antikoerper

Hintergrund:

Synonyms: Protein scribble homolog, Scribble, hScrib, Protein LAP4, SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL

Tissue Specificity: Expressed in kidney, skeletal muscles, liver, lung, breast, intestine, placenta and skin mainly in epithelial cells (at protein level).

Background: SCRIB, also known as Scribble, SCRIBL, or Scribbled homolog (Drosophila), is a scaffold protein which in humans is encoded by the SCRIB gene. In Drosophila melanogaster, SCRIB is involved in synaptic function, neuroblast differentiation, and epithelial polarization. Mechanistically, the human homolog is a scaffold protein linked to cellular differentiation centered on the regulation of epithelial as well as neuronal morphogenesis. Deficiency in SCRIB impairs many aspects of cell polarity and cell movement. SCRIB is also likely involved in establishing apical-basal polarity as well as progression from the G1 phase to S phase in the cell cycle as a result of its relationship with cell proliferation and exocytosis.

UniProt: Q14160

Pathways: Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Tube Formation, Synaptic Vesicle Exocytosis, Asymmetric Protein Localization