Galectin 10 Antikörper (AA 2-142)

Produktnummer ABIN5693147

Produktdetails anti-Galectin 10 Antikörper

Target: Galectin 10 (CLC) (Charcot-Leyden Crystal Protein (CLC))

Bindungsspezifität: AA 2-142

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Galectin 10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Marke: Picoband™

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Galectin 10 detection. Tested with WB, Direct ELISA in Human.

Immunogen: E. coli-derived human Galectin 10 recombinant protein (Position: S2-R142).

Anwendungsinformationen

Applikationshinweise:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Details zu Galectin 10

Target: Galectin 10 (CLC) (Charcot-Leyden Crystal Protein (CLC))

Andere Bezeichnung: CLC (CLC Produkte)

Synonyme: GAL10 antikoerper, Gal-10 antikoerper, LGALS10 antikoerper, LGALS10A antikoerper, LPPL_HUMAN antikoerper, Clcp antikoerper, gal-10 antikoerper, Bsf3 antikoerper, CLC antikoerper, GAL 10 antikoerper, Gal-8 antikoerper, Gal8 antikoerper, Charcot-Leyden crystal galectin antikoerper, Charcot-Leyden crystal protein antikoerper, cardiotrophin-like cytokine factor 1 antikoerper, avian beta-defensin 10 antikoerper, CLC antikoerper, Clc antikoerper, Clcf1 antikoerper, AvBD10 antikoerper

Hintergrund:

Synonyms: Galectin-10, Gal-10, Charcot-Leyden crystal protein, CLC, Eosinophil lysophospholipase, Lysolecithin acylhydrolase, CLC, LGALS10, LGALS10A

Tissue Specificity: Expressed abundantly in the bone marrow. Expressed exclusively by eosinophils and basophils. Not detected in monocytes and neutrophils. Expressed in CD25-positive regulatory T-cells (Treg) (at protein level). Found in intestinal tissue from patients with Celiac disease, expression is directly related to the histological grade of mucosal damage and to the number of eosinophils found in the duodenal lesion (at protein level). Found in sputum of patients with eosinophilic inflammatory diseases such as asthma (at protein level).

Background: Eosinophil lysophospholipase is an enzyme that in humans is encoded by the CLC gene. Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias.

UniProt: Q05315

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response