Stearoyl-Coenzyme A Desaturase 1 (SCD1) (AA 21-33) Antikörper

Produktnummer ABIN5690340

Produktdetails

Target: Stearoyl-Coenzyme A Desaturase 1 (SCD1)

Bindungsspezifität: AA 21-33

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: Recognizes mouse SCD1. Detects a band of ~41  kDa by Western Blot.

Immunogen: Synthetic peptide corresponding to aa 21-33 (A21PPSGNEREKVKT33) of mouse SCD1.

Anwendungsinformationen

Applikationshinweise: ELISA: (direct and indirect: 1:2,000-1:5,000). Western Blot: (1:2,000-1:5,000 using ECL, suggested blocking and dilution buffer is PBST containing 0.05 % Tween 20 and 5 % skim milk, suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. 0.2um-filtered solution in PBS,  pH 7.4. Contains no preservatives.

Konservierungsmittel: Without preservative

Lagerung: -20 °C

Informationen zur Lagerung: Stable for at least 6 months after receipt when stored at -20°C.

Antigendetails

Target: Stearoyl-Coenzyme A Desaturase 1 (SCD1)

Andere Bezeichnung: Stearoyl-CoA Desaturase-1 (SCD1 Produkte)

Synonyme: AA589638 antikoerper, AI265570 antikoerper, Scd antikoerper, Scd-1 antikoerper, ab antikoerper, stearoyl-Coenzyme A desaturase 1 antikoerper, Scd1 antikoerper

Hintergrund: Stearoyl-CoA desaturase (SCD) is a regulatory enzyme in lipogenesis. The enzyme is constitutively expressed in adipose tissue and is induced in liver in response to fat free, high carbohydrate diet. Several SCD isoforms (SCD1, -2, and -3) exist in the mouse. Mice with a targeted disruption of the SCD1 isoform had reduced body adiposity, increased insulin sensitivity, and resistance to diet-induced weight gain. The protection from obesity involved increased energy expenditure and increased oxygen consumption. SCD1 deficiency shows activation of lipid oxidation in addition to reduced triglyceride synthesis and storage.

Gen-ID: 20249

UniProt: P13516

Pathways: Brown Fat Cell Differentiation