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WAC Antikörper (AA 210-260)
WAC
Reaktivität: Human, Maus, Ratte
ELISA, WB, IF, IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5690321
Produktdetails anti-WAC Antikörper
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Target
Alle WAC Antikörper anzeigen
WAC
(WW Domain Containing Adaptor with Coiled-Coil (WAC))
Bindungsspezifität
Alle Epitope für WAC Antikörper
AA 210-260
Reaktivität
Alle Reaktivitäten für WAC Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für WAC Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für WAC Antikörper
Polyklonal
Konjugat
Alle Konjugate für WAC Antikörper
Dieser WAC Antikörper ist unkonjugiert
Applikation
Alle Applikationen für WAC Antikörper
ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Spezifität
At least two isoforms of WAC are known to exist, this antibody will detect the larger isoform.
Aufreinigung
WAC Antibody is affinity chromatography purified via peptide column.
Immunogen
WAC antibody was raised against a 19 amino acid peptide near the center of human WAC . The immunogen is located within amino acids 210 - 260 of WAC.
Isotyp
IgG
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Discover our top product WAC Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
WAC Antibody can be used for detection of WAC by Western blot at 1 μ,g/mL.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
WAC Antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
WAC antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Details zu WAC
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Target
WAC
(WW Domain Containing Adaptor with Coiled-Coil (WAC))
Andere Bezeichnung
WAC (WAC Produkte )
Synonyme
BM-016 antikoerper, PRO1741 antikoerper, Wwp4 antikoerper, 1110067P07Rik antikoerper, A230035H12Rik antikoerper, AI256735 antikoerper, AI256776 antikoerper, DKFZp468H162 antikoerper, wac antikoerper, wu:fc13f04 antikoerper, wu:fj68f01 antikoerper, zgc:55755 antikoerper, RGD1562407 antikoerper, zgc:101828 antikoerper, WW domain containing adaptor with coiled-coil antikoerper, WW domain containing adaptor with coiled-coil a antikoerper, WW domain containing adaptor with coiled-coil b antikoerper, WAC antikoerper, Wac antikoerper, wac antikoerper, waca antikoerper, wacb antikoerper
Hintergrund
WAC Antibody: The WW domain containing adaptor with coiled-coil protein (WAC) contains a WW domain that mediates protein-protein interactions and colocalizes with RNA splicing factor SC35. Further studies have indicated that WAC is a functional partner of the RNF20/40 complex that ubiquitinates Histone H2B, and that WAC regulates H2B ubiquitination. WAC targets RNF20/40 to associate with RNA polymerase II complex for H2B ubiquitination at active transcription sites. WAC-dependent transcription is also important for cell-cycle checkpoint activation in response to genotoxic stress.
Molekulargewicht
Predicted: 71 kDa Observed: 75 kDa
Gen-ID
51322
NCBI Accession
NP_057712
UniProt
Q9BTA9
Pathways
Chromatin Binding
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