TRIM33 Antikörper (AA 580-630)

Produktnummer ABIN5690302

Produktdetails anti-TRIM33 Antikörper

Target: TRIM33 (Tripartite Motif Containing 33 (TRIM33))

Bindungsspezifität: AA 580-630

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM33 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: TRIM33 antibody is human, mouse and rat reactive. At least two isoforms of TRIM33 are known to exist.

Aufreinigung: TRIM33 Antibody is affinity chromatography purified via peptide column.

Immunogen: TRIM33 antibody was raised against an 18 amino acid peptide near the center of human TRIM33.

The immunogen is located within amino acids 580 - 630 of TRIM33.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TRIM33 antibody can be used for detection of TRIM33 by Western blot at 1 - 2 μ,g/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TRIM33 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: TRIM33 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu TRIM33

Target: TRIM33 (Tripartite Motif Containing 33 (TRIM33))

Andere Bezeichnung: TRIM33 (TRIM33 Produkte)

Synonyme: TRIM33 antikoerper, ptc7 antikoerper, rfg7 antikoerper, tf1g antikoerper, tif1g antikoerper, tifgamma antikoerper, MGC146665 antikoerper, tif1gamma antikoerper, ECTO antikoerper, PTC7 antikoerper, RFG7 antikoerper, TF1G antikoerper, TIF1G antikoerper, TIF1GAMMA antikoerper, TIFGAMMA antikoerper, ecto antikoerper, 8030451N04Rik antikoerper, AI413936 antikoerper, Ecto antikoerper, Tif1g antikoerper, ectodermin antikoerper, mKIAA1113 antikoerper, cb1085 antikoerper, id:ibd2175 antikoerper, mon antikoerper, wu:fc17f10 antikoerper, zgc:136680 antikoerper, tripartite motif containing 33 antikoerper, tripartite motif containing 33 L homeolog antikoerper, tripartite motif-containing 33 antikoerper, TRIM33 antikoerper, trim33 antikoerper, trim33.L antikoerper, Trim33 antikoerper

Hintergrund: TRIM33 Antibody: TRIM24 (TIF1alpha), TRIM28 (TIF1beta), and TRIM33 (TIF1gamma) are three related cofactors belonging to the tripartite motif superfamily that interact with distinct transcription factors (1-2). The structure of TRIM33 is similar to TRIM24 and TRIM28, exhibiting multiple domains (RING finger, coiled coil, B boxes, PHD/TTC, and bromodomain) (3). TRIM33 functions in cell differentiation and development, playing a role in differentiation of hematopoietic cells (3). It interacts with the Smad2/3 transcription factor in hematopoietic, mesenchymal, and epithelial cell types to mediate different transcriptional effects in response to TGF-beta (4). It acts as an E3 ubiquitin-protein ligase and promotes SMAD4 ubiquitination (5).

Molekulargewicht: Predicted: 70, 124 kDa

Observed: 70 kDa

Gen-ID: 51592

NCBI Accession: NP_056990

UniProt: Q9UPN9