SLC30A8 Antikörper (N-Term)

Produktnummer ABIN5690254

Produktdetails anti-SLC30A8 Antikörper

Target: SLC30A8 (Solute Carrier Family 30 (Zinc Transporter), Member 8 (SLC30A8))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC30A8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: Two isoforms of SLC30A8 are known to exist, this antibody will detect both isoforms. This SLC30A8 antibody is predicted to not cross-react with other members of the SLC30 protein family.

Aufreinigung: SLC30A8 Antibody is affinity chromatography purified via peptide column.

Immunogen: SLC30A8 antibody was raised against a peptide corresponding to 14 amino acids near the amino terminus of human SLC30A8.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: SLC30A8 antibody can be used for Western blot at 1 - 2 μ,g/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SLC30A8 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: SLC30A8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu SLC30A8

Target: SLC30A8 (Solute Carrier Family 30 (Zinc Transporter), Member 8 (SLC30A8))

Andere Bezeichnung: SLC30A8 (SLC30A8 Produkte)

Synonyme: C820002P14Rik antikoerper, ZnT-8 antikoerper, ZnT8 antikoerper, slc30a3 antikoerper, znt8 antikoerper, ZNT8 antikoerper, E130106K10Rik antikoerper, Gm212 antikoerper, wu:fe49g03 antikoerper, RGD1305098 antikoerper, solute carrier family 30 member 8 antikoerper, solute carrier family 30 (zinc transporter), member 8 antikoerper, solute carrier family 30 (zinc transporter), member 8 L homeolog antikoerper, solute carrier family 30, member 10 antikoerper, SLC30A8 antikoerper, Slc30a8 antikoerper, slc30a8.L antikoerper, slc30a8 antikoerper, Slc30a10 antikoerper

Hintergrund: SLC30A8 Antibody: SLC30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles and is expressed at a high level in the pancreas, particularly in islets of Langerhans, and co-localizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells (1). Allelic variants of SLC30A8 have been identified as major genetic risk factors for the development of Type 2 diabetes (2), but no genetic association has been found with Type 1 diabetes (3). SLC30A8 expression in β-cells was found to be influenced by cytokine expression, particularly IFN-gamma and IL-1beta (4).

Molekulargewicht: Predicted: 35, 41 kDa

Observed: 35, 41 kDa

Gen-ID: 169026

NCBI Accession: NP_776250

UniProt: Q8IWU4

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Carbohydrate Homeostasis, Transition Metal Ion Homeostasis