PACS1 Antikörper (AA 430-480)

Produktnummer ABIN5690090

Produktdetails anti-PACS1 Antikörper

Target: PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))

Bindungsspezifität: AA 430-480

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PACS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Spezifität: PACS1 antibody is human, mouse and rat reactive. Multiple isoforms of PACS1 are known to exist. PACS1 antibody is predicted to not cross-react with PACS2.

Aufreinigung: PACS1 antibody is affinity chromatography purified via peptide column.

Immunogen: PACS1 antibody was raised against a 17 amino acid peptide near the center of human PACS1.

The immunogen is located within amino acids 430 - 480 of PACS1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: PACS1 antibody can be used for detection of PACS1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL For immunofluorescence start at 20 μ,g/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PACS1 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: PACS1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu PACS1

Target: PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))

Andere Bezeichnung: PACS1 (PACS1 Produkte)

Synonyme: MRD17 antikoerper, AI325977 antikoerper, Pacs-1 antikoerper, phosphofurin acidic cluster sorting protein 1 antikoerper, PACS1 antikoerper, Pacs1 antikoerper

Hintergrund: The phosphofurin acidic cluster sorting protein 1 (PACS1), belongs to the PACS family of cytosolic connector proteins that localize different membrane proteins to the trans-Golgi network (TGN) (1,2). Mutations in PACS1 cause defects in cranial-neural crest migration during early development, leading to a recognizable intellectual disability syndrome (3). PACS1, along with the related protein PACS2, also plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance (4).

Molekulargewicht: Predicted: 106 kDa

Observed: 105 kDa

Gen-ID: 55690

NCBI Accession: NP_060496

UniProt: Q6VY07