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ME1 Antikörper (N-Term)
ME1
Reaktivität: Human, Maus, Ratte
WB, ELISA, IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5690050
Produktdetails anti-ME1 Antikörper
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Target
Alle ME1 Antikörper anzeigen
ME1
(Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1))
Bindungsspezifität
Alle Epitope für ME1 Antikörper
N-Term
Reaktivität
Alle Reaktivitäten für ME1 Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für ME1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für ME1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für ME1 Antikörper
Dieser ME1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für ME1 Antikörper
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Spezifität
ME1 antibody is human, mouse and rat reactive. ME1 antibody is predicted not to cross-react with ME2.
Aufreinigung
ME1 antibody is affinity chromatography purified via peptide column.
Immunogen
ME1 antibody was raised against a 16 amino acid peptide near the amino terminus of human ME1. The immunogen is located within the first 50 amino acids of ME1.
Isotyp
IgG
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Alternativen
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anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (N-Term) antibody
ME1
Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Rind (Kuh), Schaf, Pferd, Schwein
WB, IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Anwendungsinformationen
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Applikationshinweise
ME1 antibody can be used for detection of ME1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
ME1 Antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
ME1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Details zu ME1
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Target
ME1
(Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1))
Andere Bezeichnung
ME1 (ME1 Produkte )
Synonyme
HUMNDME antikoerper, MES antikoerper, D9Ertd267e antikoerper, Mdh-1 antikoerper, Mod-1 antikoerper, Mod1 antikoerper, MOD1 antikoerper, ME1 antikoerper, zgc:153079 antikoerper, malic enzyme 1 antikoerper, malic enzyme 1, NADP(+)-dependent, cytosolic antikoerper, ME1 antikoerper, Me1 antikoerper, me1 antikoerper
Hintergrund
ME1, also known as NADP-ME, MES or HUMNDME, may play an important role as a housekeeping protein within the cell (1). ME1 is a 572 amino acid cytoplasmic protein that belongs to the malic enzyme family (2). It is expressed ubiquitously with highest expression in liver and white adipose tissue. ME1 functions as an NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis (3). The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles (3,4). ME1 is regulated by both thyroid hormone levels and the amount of carbohydrates in the diet (5).
Molekulargewicht
Predicted: 63 kDa Observed: 63 kDa
Gen-ID
4199
NCBI Accession
NP_002386
UniProt
P48163
Pathways
Regulation of Lipid Metabolism by PPARalpha
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