THRA Antikörper (N-Term)

Produktnummer ABIN5688666

Produktdetails anti-THRA Antikörper

Target: THRA (Thyroid Hormone Receptor, alpha (THRA))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser THRA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Protein G purified

Immunogen: Peptide corresponding to amino acid residues from the N-terminal region of human thyroid hormone receptor, a1/a2-isotype.

Klon: 2103

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: The antibody has been directly tested for reactivity in Western blots with human tissue. It is anticipated that the antibody will react with canine, mouse and rat based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: Thyroid Hormone Receptor antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Details zu THRA

Target: THRA (Thyroid Hormone Receptor, alpha (THRA))

Andere Bezeichnung: Thyroid Hormone Receptor (THRA Produkte)

Synonyme: AR7 antikoerper, CHNG6 antikoerper, EAR7 antikoerper, ERB-T-1 antikoerper, ERBA antikoerper, ERBA1 antikoerper, NR1A1 antikoerper, THRA1 antikoerper, THRA2 antikoerper, c-ERBA-1 antikoerper, C-ERBA-ALPHA antikoerper, TRalpha antikoerper, c-erba antikoerper, erba antikoerper, nr1a1-A antikoerper, thra-A antikoerper, thra1 antikoerper, TR[a]1 antikoerper, nr1a1 antikoerper, thra antikoerper, thral antikoerper, tra antikoerper, tra1 antikoerper, wu:fb59g07 antikoerper, Thra1 antikoerper, 6430529J03Rik antikoerper, AW259572 antikoerper, Erba antikoerper, Nr1a1 antikoerper, Rvr antikoerper, T3R[a] antikoerper, T3Ralpha antikoerper, Thra2 antikoerper, C-ERBA ALPHA1 antikoerper, Thra antikoerper, fTHRalphaA antikoerper, nr1a1-a antikoerper, thyroid hormone receptor, alpha antikoerper, thyroid hormone receptor, alpha L homeolog antikoerper, thyroid hormone receptor alpha a antikoerper, thyroid hormone receptor alpha antikoerper, thyroid hormone receptor alpha-A antikoerper, THRA antikoerper, thra.L antikoerper, thraa antikoerper, Thra antikoerper, tr-alpha antikoerper, LOC109641414 antikoerper

Hintergrund: Thyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as learning and memory (Ambrogini et al., 2005, Chan and Kilby, 2000). Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors TRalpha1, TRalpha2, TRbeta1 and TRbeta2. TRalpha1, TRbeta1 and TRbeta2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain (Constantinou et al., 2005).

Molekulargewicht: 50/58 kDa

Gen-ID: 7067

UniProt: P10827

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Maintenance of Protein Location, Skeletal Muscle Fiber Development