SPINT2 Antikörper (Internal Region)

Produktnummer ABIN568704

Produktdetails anti-SPINT2 Antikörper

Target: SPINT2 (serine Peptidase Inhibitor, Kunitz Type, 2 (SPINT2))

Bindungsspezifität: Internal Region

Reaktivität: Human, Hund, Rind (Kuh)

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser SPINT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: C-PSAPRRQDSE DH

Spezifität: This antibody is expected to recognize both reported isoforms (NP_066925.1, NP_001159575.1).

Kreuzreaktivität (Details): Species reactivity (expected):Dog, Cow.
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_066925.1 and NP_001159575.1. Genename: SPINT2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu SPINT2

Target: SPINT2 (serine Peptidase Inhibitor, Kunitz Type, 2 (SPINT2))

Andere Bezeichnung: SPINT2 / HAI2 (SPINT2 Produkte)

Synonyme: HAI-2 antikoerper, Pb antikoerper, DIAR3 antikoerper, HAI2 antikoerper, Kop antikoerper, PB antikoerper, AL024025 antikoerper, C76321 antikoerper, serine peptidase inhibitor, Kunitz type, 2 antikoerper, serine peptidase inhibitor, Kunitz type 2 antikoerper, serine protease inhibitor, Kunitz type 2 antikoerper, Spint2 antikoerper, SPINT2 antikoerper

Hintergrund: HAI-2 (SPINT2) is a candidate tumour suppressor gene that is frequently hypermethylated and underexpressed in Human HCCs, and the KD-1 domain of HAI-2 is the key region responsible for its anti-invasive function. It is also implicated in Human cervical cancer. SPINT2 is an inhibitor of HGF activator. SPINT2 also inhibits plasmin, plasma and tissue kallikrein, and factor XIa.Synonyms: HAI-2, Hepatocyte growth factor activator inhibitor type 2, Kunitz-type protease inhibitor 2, Placental bikunin

Gen-ID: 10653

NCBI Accession: NP_066925

UniProt: O43291