Ancient Ubiquitous Protein 1 Antikörper (AA 229-410)

Produktnummer ABIN5684097

Produktdetails anti-Ancient Ubiquitous Protein 1 Antikörper

Target: Ancient Ubiquitous Protein 1 (Aup1)

Bindungsspezifität: AA 229-410

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Ancient Ubiquitous Protein 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human AUP1 (AA: 229-410) expressed in E. coli.

Klon: 7G4A6

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: N/A, IHC: N/A

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu Ancient Ubiquitous Protein 1

Target: Ancient Ubiquitous Protein 1 (Aup1)

Andere Bezeichnung: AUP1 (Aup1 Produkte)

Synonyme: AA589454 antikoerper, wu:fc37d06 antikoerper, zgc:73323 antikoerper, zgc:77755 antikoerper, AUP1, lipid droplet regulating VLDL assembly factor antikoerper, ancient ubiquitous protein 1 antikoerper, ancient ubiquitous protein 1 S homeolog antikoerper, AUP1 antikoerper, aup1 antikoerper, Aup1 antikoerper, aup1.S antikoerper

Hintergrund: The protein encoded this gene is involved in several pathways including quality control of misfolded proteins in the endoplasmic reticulum and lipid droplet accumulation. Lipid droplets are organelles in the cytoplasm that store neutral lipids such as cholesterol esters and trigylycerides to prevent the overabundance of free cholesterol and fatty acids in cells, but also to act as storage for other metabolic processes, such as membrane biogenesis. Reduced expression of this gene results in reduced lipid droplet clustering, a function that is dependent on ubiquitination of the protein. This protein contains multiple domains including a hydrophobic N-terminal domain, an acetyltranferase domain, a ubiquitin-binding CUE domain, and a UBE2B2-binding domain (G2BR). Alternative splicing results in multiple transcript variants.

Molekulargewicht: 53 kDa

Gen-ID: 550

HGNC: 27180