ACVR2A Antikörper (C-Term)

Produktnummer ABIN5671355

Produktdetails anti-ACVR2A Antikörper

Target: ACVR2A (Activin A Receptor, Type IIA (ACVR2A))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Ziege, Meerschweinchen, Pferd, Kaninchen, Schaf, Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACVR2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AYLHEDIPGL KDGHKPAISH RDIKSKNVLL KNNLTACIAD FGLALKFEAG

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against AVR2A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human AVR2A

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ACVR2A

Target: ACVR2A (Activin A Receptor, Type IIA (ACVR2A))

Andere Bezeichnung: AVR2A (ACVR2A Produkte)

Synonyme: ACVR2 antikoerper, ACVR2A antikoerper, XSTK9 antikoerper, actrii antikoerper, acvr2 antikoerper, ACTRII antikoerper, Acvr2 antikoerper, rActR-II antikoerper, actr2a antikoerper, acvr2a antikoerper, wu:fa02e10 antikoerper, ActrIIa antikoerper, TactrII antikoerper, activin A receptor type 2A antikoerper, activin A receptor type 2A L homeolog antikoerper, activin A receptor type 2Aa antikoerper, activin receptor IIA antikoerper, ACVR2A antikoerper, acvr2a antikoerper, Acvr2a antikoerper, acvr2a.L antikoerper, acvr2aa antikoerper

Hintergrund: This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene.

Alias Symbols: ACVR2A, ACVR2,

Protein Interaction Partner: BMP10, GDF2, ACVR1, INHBA, PEG10, ERBB2IP, UBC, IGSF1, MAGI2, TCTEX1D4, SYNJ2BP, GDF9, ACVRL1, INHBC, GDF5, TGFBR3, INHBB, ENG, BMP7, BMP6, ACVR1B, INHA,

Protein Size: 513

Gen-ID: 92

NCBI Accession: NP_001607

UniProt: P27037