Rekombinanter C-Type Lectin Domain Family 4, Member M (CLEC4M) Antikörper

Produktnummer ABIN5668173

Produktdetails

Target: C-Type Lectin Domain Family 4, Member M (CLEC4M)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (IHC), Flow Cytometry (FACS)

Spezifität: Human CD299, which is an oligomeric type II transmembrane protein with a C-type lectin extracellular domain, the expression of which is restricted to immature DC, macrophages in the lung, and endothelial cells in the liver. It binds ICAM-3 and ICAM-7 to mediate the interaction of DC with T lymphocytes and endothelial cells in the initial stages of immune response and in the migratory behavior of DC. CD299 also binds the gp120 protein of HIV and the E2 envelope protein of HCV, thereby playing a role in viral infection.

Produktmerkmale:

OriginalSpeciesName: Mouse

OriginalFormat: IgG1

Aufreinigung: Purified antibody.

Immunogen: CD299

Klon: 16E7

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Antigendetails

Target: C-Type Lectin Domain Family 4, Member M (CLEC4M)

Andere Bezeichnung: DC-SIGNR (CLEC4M Produkte)

Synonyme: CD209L antikoerper, CD299 antikoerper, DC-SIGN2 antikoerper, DC-SIGNR antikoerper, DCSIGNR antikoerper, HP10347 antikoerper, L-SIGN antikoerper, LSIGN antikoerper, CD209B antikoerper, C-type lectin domain family 4 member M antikoerper, CLEC4M antikoerper

Hintergrund: CD299, C-type lectin domain family 4 member M, CD209 antigen-like protein 1, DC-SIGN-related protein, CLEC4M, Dendritic cell-specific ICAM-3-grabbing non-integrin 2, DC-SIGN2, Liver/lymph node-specific ICAM-3-grabbing non-integrin, L-SIGN

UniProt: Q9H2X3