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Rekombinanter TNF alpha (Adalimumab Biosimilar) Antikörper

Reaktivität: Human ELISA, IF, IHC, BR Wirt: Kaninchen Monoclonal D2E7 unconjugated Recombinant Antibody
Produktnummer ABIN5668146
  • Target Alle TNF alpha (Adalimumab Biosimilar) Produkte
    TNF alpha (Adalimumab Biosimilar)
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    Human
    Wirt
    • 2
    • 2
    • 1
    • 1
    Kaninchen
    Klonalität
    • 6
    Monoklonal
    Konjugat
    • 6
    Dieser TNF alpha (Adalimumab Biosimilar) Antikörper ist unkonjugiert
    Applikation
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Blocking Reagent (BR)
    Spezifität
    Binds to soluble TNF-alpha, but not to lymphotoxin (TNF beta).
    Produktmerkmale

    OriginalSpeciesName: Human

    OriginalFormat: IgG1

    Aufreinigung
    Purified antibody.
    Reinheit
    > 98 % as determined by SDS-PAGE
    Endotoxin-Niveau
    Endotoxin is < 1.0 EU/mg as determined by the LAL method
    Immunogen
    This antibody was generated by affinity maturation from the 2SD4 scFv, which in turn was selected on human TNF alpha by guided phage-display technology, using the murine anti-hTNF alpha antibody Mab32 as a template (c.f. also US Patent 6090382).
    Klon
    D2E7
    Isotyp
    IgG kappa
  • Applikationshinweise
    Adalimumab binds specifically to TNF and neutralizes the biological function of TNF by blocking its interaction with the p55 and p75 cell surface TNF receptors.
    Kommentare

    NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar. This chimeric rabbit antibody was made using the variable domain sequences of the original human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % Proclin 300.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Target
    TNF alpha (Adalimumab Biosimilar)
    Abstract
    TNF alpha (Adalimumab Biosimilar) Produkte
    Synonyme
    DIF antikoerper, TNF-alpha antikoerper, TNFA antikoerper, TNFSF2 antikoerper, tumor necrosis factor antikoerper, TNF antikoerper
    Substanzklasse
    Biosimilar
    Hintergrund
    Tumor necrosis factor alpha
    UniProt
    P01375
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