APLP1 Antikörper (AA 505-539)

Produktnummer ABIN5647485

Produktdetails anti-APLP1 Antikörper

Target: APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

Bindungsspezifität: AA 505-539

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APLP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 505-539 from human Amyloid-like protein 1 was used as the immunogen for the APLP1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the APLP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. WB: 1:1000-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the APLP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu APLP1

Target: APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

Andere Bezeichnung: APLP1 (APLP1 Produkte)

Synonyme: aplp antikoerper, MGC115336 antikoerper, APLP antikoerper, Aplp1_retired antikoerper, RGD1561211 antikoerper, amyloid beta precursor like protein 1 antikoerper, amyloid beta precursor like protein 1 L homeolog antikoerper, amyloid beta (A4) precursor-like protein 1 antikoerper, APLP1 antikoerper, aplp1.L antikoerper, aplp1 antikoerper, Aplp1 antikoerper

Hintergrund: Amyloid-like protein 1 may play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I.

UniProt: P51693

Pathways: cAMP Metabolic Process