NMNAT1 Antikörper (AA 171-201)

Produktnummer ABIN5647421

Produktdetails anti-NMNAT1 Antikörper

Target: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Bindungsspezifität: AA 171-201

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NMNAT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität (Details): Expected species reactivity: Bovine

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 171-201 from the human protein was used as the immunogen for the NMNAT1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western blot: 1:1000-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the NMNAT1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu NMNAT1

Target: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Andere Bezeichnung: NMNAT1 / Nicotinamide-nucleotide adenylyltransferase 1 (NMNAT1 Produkte)

Synonyme: id:ibd5068 antikoerper, im:7144541 antikoerper, zgc:110243 antikoerper, LCA9 antikoerper, NMNAT antikoerper, PNAT1 antikoerper, 2610529L11Rik antikoerper, 5730441G13Rik antikoerper, D4Cole1e antikoerper, nmnat antikoerper, nicotinamide mononucleotide adenylyltransferase 1 antikoerper, nicotinamide nucleotide adenylyltransferase 1 antikoerper, CpipJ_CPIJ015320 antikoerper, PTRG_06486 antikoerper, nmnat1 antikoerper, NMNAT1 antikoerper, Nmnat1 antikoerper

Hintergrund: Nicotinamide mononucleotide adenylyltransferase 1 catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form, nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, prefers NAD(+) and NAAD as substrates and degrades NADH, nicotinic acid adenine dinucleotide phosphate (NHD) and nicotinamide guanine dinucleotide (NGD) less effectively. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+). Protects against axonal degeneration following mechanical or toxic insults.

Gen-ID: 64802

UniProt: Q9HAN9