CD41, CD61 Antikörper
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- Target Alle CD41, CD61 Antikörper anzeigen
- CD41, CD61 (CD41,CD61)
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD41, CD61 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)
- Spezifität
- The mouse monoclonal antibody PAC-1 recognizes an extracellular activation-induced conformational epitope PAC-1 on CD41/CD61 complex (gpIIb/IIIa), also known as integrin alpha IIb beta 3, a receptor which mediates platelet aggregation.
- Kreuzreaktivität (Details)
- Human
- Aufreinigung
- Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).
- Reinheit
- > 95 % (by SDS-PAGE)
- Immunogen
- Human platelets
- Klon
- PAC-1
- Isotyp
- IgM kappa
- Top Product
- Discover our top product CD41, CD61 Primärantikörper
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anti-CD41,CD61 antibody
Reaktivität: Human, Rind (Kuh) FACS, IP, ELISA, ICC Wirt: Maus Monoclonal IVA30 unconjugated
anti-CD41,CD61 antibody (PE)Reaktivität: Human FACS Wirt: Maus Monoclonal PAC-1 PE
anti-CD41,CD61 antibody (PerCP)Reaktivität: Human FACS Wirt: Maus Monoclonal PAC-1 PerCP
anti-CD41,CD61 antibody (FITC)Reaktivität: Human FACS Wirt: Maus Monoclonal PAC-1 FITC
anti-CD41,CD61 antibodyReaktivität: Human FACS, IF, DNA Mic Wirt: Maus Monoclonal A2A9-6 unconjugated
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- Applikationshinweise
- Flow cytometry: Recommended dilution: 2-4 μg/mL.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- Target
- CD41, CD61 (CD41,CD61)
- Andere Bezeichnung
- CD41/CD61 (CD41, CD61 Produkte)
- Hintergrund
- CD41 (platelet glycoprotein IIb, integrin alpha IIb) is composed of two subunits (120 kDa transmembrane alpha chain and 23 kDa extracellular beta chain) and interacts with CD61 (platelet glycoprotein IIIa, integrin beta 3) in the presence of calcium to form a functional adhesive protein receptor. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin, and it is involved in platelet aggregation.,platelet GPIIb, Integrin alpha-Iib, GPalpha IIb, GPIIb, GT, GP3A, platelet GPIIIa
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