ELISA. Western blot: 1: 500 to 1: 1000. An approximate 40 kDa band can be detected, whichrepresents the pro-enzyme of DNase II. Immunflourescence. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
PBS containing 0.02 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
DAPK3 antikoerper, dapk3 antikoerper, wu:fc25b08 antikoerper, si:dkey-57k2.5 antikoerper, MGC114871 antikoerper, ZIP antikoerper, ZIPK antikoerper, dlk antikoerper, Dapkl antikoerper, death associated protein kinase 3 antikoerper, death-associated protein kinase 3 antikoerper, death-associated protein kinase 3 L homeolog antikoerper, DAPK3 antikoerper, dapk3 antikoerper, dapk3.L antikoerper, Dapk3 antikoerper
Hintergrund
Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. A novel serine/threonine kinase that mediates apoptosis was recently identified and designated ZIP kinase . ZIP kinase contains an N-terminal kinase domain and a C-terminal leucine zipper structure and binds to ATF4 that is a member of ATF/CREB family. ZIP kinase has high sequence homology to DAP kinase (death-associated protein kinase), which is a mediator of apoptosis induced by gamma interferon. Overexpression of ZIP kinase induces apoptosis. ZIP and DAP kinases represent a novel kinase family, which mediates apoptosis through their catalytic activities. The messenger RNA was ubiquitously expressed in various tissues .Synonyms: DAP kinase 3, DAP-like kinase, DLK, Death-associated protein kinase 3, ZIP-kinase