Klra3 Antikörper (C-Term)

Produktnummer ABIN500132

Produktdetails anti-Klra3 Antikörper

Target: Klra3 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 3 (Klra3))

Bindungsspezifität: C-Term

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Klra3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects KLRA3. It may cross-react with other LY49 receptors.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse.

Aufreinigung: Peptide affinity chromatography

Immunogen: KLRA3 antibody was raised against a 14 amino acid peptide near the carboxy terminus of mouse KLRA3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu Klra3

Target: Klra3 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 3 (Klra3))

Andere Bezeichnung: KLRA3 (Klra3 Produkte)

Synonyme: 5E6 antikoerper, Ly49c antikoerper, NK-2.1 antikoerper, Nk-2 antikoerper, Nk2 antikoerper, Nk2.1 antikoerper, killer cell lectin-like receptor, subfamily A, member 3 antikoerper, Klra3 antikoerper

Hintergrund: KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide -receptive H-2Kb.Synonyms: 5E6, Killer cell lectin-like receptor 3, Ly-49c, Ly49C, Lymphocyte antigen 49c, T-cell surface glycoprotein Ly-49C

Gen-ID: 16640

NCBI Accession: NP_034781

UniProt: Q64329