ARHGDIB Antikörper (N-Term)

Produktnummer ABIN499142

Produktdetails anti-ARHGDIB Antikörper

Target: ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

Bindungsspezifität: N-Term

Reaktivität: Human, Rind (Kuh), Hund, Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser ARHGDIB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: TEKAPEPHVE -C

Spezifität: Recognizes ARHGDIB.

Kreuzreaktivität (Details): Species reactivity (expected):Canine, Pig, Bovine.
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the N Terminus of the protein sequence according to NP_001166.3. Genename: ARHGDIB

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Limit Dilution: 1/4000. Western blot: 1-3 μg/mL. This antibody detects a band of approx. 26 kDa in lysates of cell lineJurkat.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ARHGDIB

Target: ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

Andere Bezeichnung: ARHGDIB / D4-GDI (ARHGDIB Produkte)

Synonyme: ARHGDIB antikoerper, zgc:65966 antikoerper, arhgdib antikoerper, MGC69067 antikoerper, gdia2 antikoerper, rhodgi-2 antikoerper, rhodgi2 antikoerper, D4 antikoerper, GDIA2 antikoerper, GDID4 antikoerper, LYGDI antikoerper, Ly-GDI antikoerper, RAP1GN1 antikoerper, RhoGDI2 antikoerper, Gdid4 antikoerper, Rho GDP dissociation inhibitor (GDI) gamma antikoerper, Rho GDP dissociation inhibitor (GDI) beta S homeolog antikoerper, Rho GDP dissociation inhibitor beta antikoerper, Rho GDP dissociation inhibitor (GDI) beta antikoerper, Rho, GDP dissociation inhibitor (GDI) beta antikoerper, arhgdig antikoerper, arhgdib.S antikoerper, ARHGDIB antikoerper, arhgdib antikoerper, Arhgdib antikoerper

Hintergrund: D4-GDI belongs to the family of Rho GDIs or GDP dissociation inhibitors for the Rho/Rac family of small G proteins, consisting of RhoGDI 1, D4 GDI/RhoGDI2 and Rho GDI3. It inhibits the release of GDP from the Rho proteins, essential for GTP loading and activation of GTPase activity. D4 GDI is located in the cytoplasm and in involved in the regulation of the membrane association and dissociation cycle of Rho/Rac proteins. It is known to be a substrate for caspase 3 during Fas mediated apoptosis.Synonyms: GDIA2, GDID4, Ly-GDI, RAP1GN1, Rho GDI 2, Rho GDP-dissociation inhibitor 2, Rho-GDI beta, RhoGDI2

Molekulargewicht: 23.0kDa (NP_001166.3)

Gen-ID: 397

NCBI Accession: NP_001166

UniProt: P52566

Pathways: Caspase Kaskade in der Apoptose