CENPQ Antikörper

Produktnummer ABIN401060

Produktdetails anti-CENPQ Antikörper

Target: CENPQ (Centromere Protein Q (CENPQ))

Reaktivität: Human, Maus, Ratte, Schwein, Rind (Kuh), Hund, Pferd, Makake

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CENPQ Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Spezifität: This antibody is specific for CENP-Q protein.

Kreuzreaktivität (Details): Species reactivity (expected):Macaque, Horse, Bovine, Canine, Porcine, Mouse, Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on protein A

Immunogen: Prepared from whole rabbit serum produced by repeated immunizations with full-length human CENP-Q recombinant protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 20,000 - 1: 30,000. Immunofluorescence. Western Blot: 1: 2,000 - 1: 2,500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.15 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu CENPQ

Target: CENPQ (Centromere Protein Q (CENPQ))

Andere Bezeichnung: CENP-Q (CENPQ Produkte)

Synonyme: C6orf139 antikoerper, CENP-Q antikoerper, 2610528M18Rik antikoerper, centromere protein Q antikoerper, CENPQ antikoerper, cenpq antikoerper, Cenpq antikoerper

Hintergrund: Cenp-Q (also known as centromere protein Q or CENPQ) is a nuclear/centromeric protein that is one of the critical components that constitutes the CENP-O complex at the kinetochores and appears to stabilize PBIP1/CENP-U(50)/MLF1IP in the complex. This complex is important for proper recruitment of polo-like kinase 1 (Plk1) to the mitotic kinetochores. A failure in this process results in improper microtubule attachment to the kinetochores and chromosome missegregation that ultimately lead to aneuploidy.Synonyms: C6orf139, CENPQ, Centromere protein Q, chromosome 6 open reading frame 139

Gen-ID: 55166

NCBI Accession: NP_060602

UniProt: Q7L2Z9