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NMDA 1 Receptor Antikörper (pSer890)

NMDA R1 Reaktivität: Human, Ratte, Maus IHC (p), IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5540835
  • Target Alle NMDA 1 Receptor (NMDA R1) Antikörper anzeigen
    NMDA 1 Receptor (NMDA R1) (NMDA Receptor 1 (NMDA R1))
    Bindungsspezifität
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer890
    Reaktivität
    • 19
    • 16
    • 15
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 18
    • 5
    Kaninchen
    Klonalität
    • 18
    • 5
    Polyklonal
    Konjugat
    • 23
    Dieser NMDA 1 Receptor Antikörper ist unkonjugiert
    Applikation
    • 19
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    The antibody detects endogenous levels of NMDAR1 only when phosphorylated at serine 890.
    Aufreinigung
    Affinity chromatography using epitope-specific peptide
    Immunogen
    Peptide sequence around phosphorylation site of Serine 890(A-S-S(p)-F-K) derived from Human NMDAR1 (KLH-conjugated)
    Top Product
    Discover our top product NMDA R1 Primärantikörper
  • Applikationshinweise
    Immunohistochemistry on paraffin sections: 1:50~1:100. Immunofluorescence: 1:100~1:200.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
    Haltbarkeit
    12 months
  • Target
    NMDA 1 Receptor (NMDA R1) (NMDA Receptor 1 (NMDA R1))
    Andere Bezeichnung
    nmda receptor 1 (NMDA R1 Produkte)
    Synonyme
    CG2902 antikoerper, DMNMDAR1 antikoerper, DNMDAR-I antikoerper, DNmdar antikoerper, DmelNmdar1 antikoerper, Dmel\\CG2902 antikoerper, DrNR1 antikoerper, NMDA antikoerper, NMDA R1 antikoerper, NMDAR1 antikoerper, NMdar1 antikoerper, NR1 antikoerper, NRI antikoerper, Nmdar antikoerper, dNR1 antikoerper, dnmdar-I antikoerper, nmr antikoerper, NMDA receptor 1 antikoerper, Nmdar1 antikoerper
    Hintergrund
    NMDA receptors are members of the ionotropic class of glutamate receptors, which also includes Kainate and AMPA receptors. NMDA receptors consist of NR1 subunits combined with one or more NR2 (A-D) or NR3 (A-B) subunits. The ligand-gated channel is permeable to cations including Ca2+, and at resting membrane potentials NMDA receptors are inactive due to a voltage-dependent blockade of the channel pore by Mg2+. NMDA receptor activation, which requires binding of glutamate and glycine, leads to an influx of Ca2+ into the postsynaptic region where it activates several signaling cascades, including pathways leading to the induction of long-term potentiation (LTP) and depression (LTD). NMDA receptors have a critical role in excitatory synaptic transmission and plasticity in the CNS. They govern a range of physiological conditions including neurological disorders caused by excitotoxic neuronal injury, psychiatric disorders and neuropathic pain syndromes.
    UniProt
    Q05586
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