WTIP Antikörper (AA 243-271)

Produktnummer ABIN5538334

Produktdetails anti-WTIP Antikörper

Target: WTIP (Wilms Tumor 1 Interacting Protein (WTIP))

Bindungsspezifität: AA 243-271

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WTIP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This WTIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-271 amino acids of human WTIP.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For IHC-P starting dilution is: 1:10~50

For WB starting dilution is: 1:1000

For IF starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu WTIP

Target: WTIP (Wilms Tumor 1 Interacting Protein (WTIP))

Andere Bezeichnung: WTIP (WTIP Produkte)

Synonyme: RGD1306411 antikoerper, si:ch211-79l17.3 antikoerper, WT1 interacting protein antikoerper, Wilms tumor 1 interacting protein antikoerper, WT1 interacting protein L homeolog antikoerper, WT1-interacting protein antikoerper, Wtip antikoerper, WTIP antikoerper, wtip antikoerper, wtip.L antikoerper

Hintergrund: WTIP may monitor slit diaphragm protein assembly, a specialized adherens junction characteristic of podocytes. In case of podocyte injury, it shuttles into the nucleus and acts as a transcription regulator that represses WT1-dependent transcription regulation, thereby translating changes in slit diaphragm structure into altered gene expression and a less differentiated phenotype (By similarity).

Molekulargewicht: 45 kDa

Gen-ID: 126374

UniProt: A6NIX2