This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This PTPN14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 862-890 amino acids from the C-terminal region of human PTPN14.
PTPN14
Reaktivität: Human
WB, IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
For WB starting dilution is: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
PTPN14
(Protein tyrosine Phosphatase, Non-Receptor Type 14 (PTPN14))
PEZ antikoerper, PTP36 antikoerper, C130080N23Rik antikoerper, OTTMUSG00000022087 antikoerper, protein tyrosine phosphatase, non-receptor type 14 antikoerper, PTPN14 antikoerper, Ptpn14 antikoerper
Hintergrund
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia.