SRSF2 Antikörper (AA 76-105)

Produktnummer ABIN5537524

Produktdetails anti-SRSF2 Antikörper

Target: SRSF2 (serine/arginine-Rich Splicing Factor 2 (SRSF2))

Bindungsspezifität: AA 76-105

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRSF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This SFRS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-105 amino acids from the Central region of human SFRS2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu SRSF2

Target: SRSF2 (serine/arginine-Rich Splicing Factor 2 (SRSF2))

Andere Bezeichnung: SFRS2 (SRSF2 Produkte)

Synonyme: PR264 antikoerper, SC-35 antikoerper, SC35 antikoerper, SFRS2 antikoerper, SFRS2A antikoerper, SRp30b antikoerper, D11Wsu175e antikoerper, MRF-1 antikoerper, Pr264 antikoerper, Sfrs10 antikoerper, Sfrs2 antikoerper, pr264 antikoerper, sc-35 antikoerper, sc35 antikoerper, sfrs2 antikoerper, sfrs2a antikoerper, srp30b antikoerper, serine and arginine rich splicing factor 2 antikoerper, serine/arginine-rich splicing factor 2 antikoerper, serine/arginine-rich splicing factor 2 L homeolog antikoerper, SRSF2 antikoerper, Srsf2 antikoerper, srsf2.L antikoerper

Hintergrund: SFRS2 is necessary for the splicing of pre-mRNA. The protein is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. And it interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. It binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5'-GTTCGAGTA-3' and can bind to beta-globin mRNA and commit it to the splicing pathway.

Molekulargewicht: 25 kDa

Gen-ID: 6427

UniProt: Q01130