SEC63 Antikörper (N-Term)

Produktnummer ABIN5537506

Produktdetails anti-SEC63 Antikörper

Target: SEC63 (SEC63 Homolog (SEC63))

Bindungsspezifität: AA 139-168, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SEC63 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SEC63 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 139-168 amino acids from the N-terminal region of human SEC63.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu SEC63

Target: SEC63 (SEC63 Homolog (SEC63))

Andere Bezeichnung: SEC63 (SEC63 Produkte)

Synonyme: DNAJC23 antikoerper, ERdj2 antikoerper, PRO2507 antikoerper, SEC63L antikoerper, 5730478J10Rik antikoerper, AI649014 antikoerper, AW319215 antikoerper, SEC63-like antikoerper, zgc:92718 antikoerper, SEC63 homolog, protein translocation regulator antikoerper, SEC63-like (S. cerevisiae) antikoerper, SEC63 homolog, protein translocation regulator L homeolog antikoerper, SEC63 antikoerper, Sec63 antikoerper, sec63 antikoerper, sec63.L antikoerper

Hintergrund: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.

Molekulargewicht: 88 kDa

Gen-ID: 11231

UniProt: Q9UGP8

Pathways: ER-Nucleus Signaling