PUM2 Antikörper (N-Term)

Produktnummer ABIN5537384

Produktdetails anti-PUM2 Antikörper

Target: PUM2 (Pumilio Homolog 2 (Drosophila) (PUM2))

Bindungsspezifität: AA 133-162, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PUM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PUM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-162 amino acids from the N-terminal region of human PUM2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.32 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PUM2

Target: PUM2 (Pumilio Homolog 2 (Drosophila) (PUM2))

Andere Bezeichnung: PUM2 (PUM2 Produkte)

Synonyme: pum-2 antikoerper, 5730503J23Rik antikoerper, Pumm2 antikoerper, mKIAA0235 antikoerper, PUMH2 antikoerper, PUML2 antikoerper, pumilio RNA binding family member 2 antikoerper, pumilio RNA-binding family member 2 antikoerper, pum2 antikoerper, Pum2 antikoerper, PUM2 antikoerper

Hintergrund: PUM2 is a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. This protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of this protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation.

Molekulargewicht: 114 kDa

Gen-ID: 23369

UniProt: Q8TB72

Pathways: Ribonucleoprotein Complex Subunit Organization