PTGIS Antikörper (C-Term)

Produktnummer ABIN5536967

Produktdetails anti-PTGIS Antikörper

Target: PTGIS (Prostaglandin I2 (Prostacyclin) Synthase (PTGIS))

Bindungsspezifität: AA 472-500, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTGIS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This CYP8A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 472-500 amino acids from the C-terminal region of human CYP8A1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PTGIS

Target: PTGIS (Prostaglandin I2 (Prostacyclin) Synthase (PTGIS))

Andere Bezeichnung: CYP8A1 (PTGIS Produkte)

Synonyme: CYP8 antikoerper, CYP8A1 antikoerper, PGIS antikoerper, PTGI antikoerper, Cyp8 antikoerper, Cyp8a1 antikoerper, Pgis antikoerper, ptgisl antikoerper, PTGIS antikoerper, prostaglandin I2 synthase antikoerper, prostaglandin I2 (prostacyclin) synthase antikoerper, prostacyclin synthase antikoerper, PTGIS antikoerper, Ptgis antikoerper, ptgis antikoerper, VDBG_06319 antikoerper

Hintergrund: CYP8A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis.

Molekulargewicht: 57 kDa

Gen-ID: 5740

UniProt: Q16647