JHDM1D Antikörper (AA 290-316)

Produktnummer ABIN5536733

Produktdetails anti-JHDM1D Antikörper

Target: JHDM1D (Jumonji C Domain-Containing Histone Demethylase 1 Homolog D (JHDM1D))

Bindungsspezifität: AA 290-316

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser JHDM1D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This JHDM1D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-316 amino acids from the Central region of human JHDM1D.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu JHDM1D

Target: JHDM1D (Jumonji C Domain-Containing Histone Demethylase 1 Homolog D (JHDM1D))

Andere Bezeichnung: JHDM1D (JHDM1D Produkte)

Synonyme: A630082K20Rik antikoerper, BB041802 antikoerper, ENSMUSG00000073143 antikoerper, Kdm7a antikoerper, mKIAA1718 antikoerper, KDM7A antikoerper, DrKDM7b antikoerper, im:7141664 antikoerper, Jhdm1d antikoerper, JHDM1D antikoerper, jhdm1d antikoerper, kdm7 antikoerper, kdm7a antikoerper, lysine (K)-specific demethylase 7A antikoerper, lysine demethylase 7A antikoerper, lysine (K)-specific demethylase 7Ab antikoerper, lysine (K)-specific demethylase 7A L homeolog antikoerper, Kdm7a antikoerper, KDM7A antikoerper, kdm7ab antikoerper, kdm7a.L antikoerper

Hintergrund: JHDM1D histone demethylase that specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3, thereby playing a central role in histone code. This specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. This demethylates H3K9me2 in absence of H3K4me3.

Molekulargewicht: 107 kDa

Gen-ID: 80853

UniProt: Q6ZMT4