GJA4 Antikörper (C-Term)

Produktnummer ABIN5536706

Produktdetails anti-GJA4 Antikörper

Target: GJA4 (Gap Junction Protein, alpha 4, 37kDa (GJA4))

Bindungsspezifität: AA 303-333, C-Term

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GJA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This Connexin 37 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 303-333 amino acids from the C-terminal region of human Connexin 37.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.15 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu GJA4

Target: GJA4 (Gap Junction Protein, alpha 4, 37kDa (GJA4))

Andere Bezeichnung: Connexin 37 (GJA4 Produkte)

Synonyme: AU020209 antikoerper, AW558810 antikoerper, Cnx37 antikoerper, Cx37 antikoerper, Gja-4 antikoerper, CXN37 antikoerper, CX37 antikoerper, Cx39 antikoerper, ggCx39 antikoerper, cx41 antikoerper, gja4 antikoerper, gap junction protein alpha 4 antikoerper, gap junction protein, alpha 4 antikoerper, gap junction protein, alpha 4, 37kDa antikoerper, gap junction protein alpha 4 L homeolog antikoerper, GJA4 antikoerper, Gja4 antikoerper, gja4.L antikoerper

Hintergrund: Gap junctions permit direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular communication. Gap junction channels consist of connexin protein subunits encoded by a multigene family. Erythrokeratodermia variabilis (EKV) is an autosomal dominant disorder of keratinization characterized by migratory erythematous lesions and fixed keratotic plaques. Mutations in the GJB3 gene have been reported in some but not all families, although it has been postulated that the absence of connexin 30.3 can be compensated by other connexins.

Molekulargewicht: 37 kDa

Gen-ID: 2701

UniProt: P35212

Pathways: Cell-Cell Junction Organization