GNRH1 Antikörper (N-Term)

Produktnummer ABIN5536391

Produktdetails anti-GNRH1 Antikörper

Target: GNRH1 (Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone) (GNRH1))

Bindungsspezifität: AA 49-77, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GNRH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GNRHR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-77 amino acids from the N-terminal region of human GNRHR.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu GNRH1

Target: GNRH1 (Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone) (GNRH1))

Andere Bezeichnung: GNRH (GNRH1 Produkte)

Synonyme: GNRH antikoerper, GRH antikoerper, HH12 antikoerper, LHRH antikoerper, LNRH antikoerper, Gnrh antikoerper, Gnrh2 antikoerper, Lhrh1 antikoerper, Lnrh antikoerper, hpg antikoerper, Gnrha antikoerper, Lhrh antikoerper, Rgnrhg1 antikoerper, CGNRH-I antikoerper, GnRH-I antikoerper, GnRH antikoerper, gnrh antikoerper, gnrh1 antikoerper, grh antikoerper, lhrh antikoerper, lnrh antikoerper, mdGnRH antikoerper, mdgnrh antikoerper, mfGnRH antikoerper, gonadotropin releasing hormone 1 antikoerper, gonadotropin releasing hormone 1 L homeolog antikoerper, prepro-gonadotropin-releasing hormone antikoerper, GNRH1 antikoerper, Gnrh1 antikoerper, gnrh1.L antikoerper, gnrh1 antikoerper

Hintergrund: This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene.

Molekulargewicht: 38 kDa

Gen-ID: 2798

UniProt: P30968

Pathways: Hormone Activity