Connexin 31 Antikörper (C-Term)

Produktnummer ABIN5536021

Produktdetails anti-Connexin 31 Antikörper

Target: Connexin 31 (GJB3) (Gap Junction Protein, beta 3, 31kDa (GJB3))

Bindungsspezifität: AA 227-257, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Connexin 31 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This Connexin 31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-257 amino acids from the C-terminal region of human Connexin 31.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu Connexin 31

Target: Connexin 31 (GJB3) (Gap Junction Protein, beta 3, 31kDa (GJB3))

Andere Bezeichnung: Connexin 31 (GJB3 Produkte)

Synonyme: CX31 antikoerper, DFNA2 antikoerper, DFNA2B antikoerper, EKV antikoerper, Cnx31 antikoerper, Cx31 antikoerper, D4Wsu144e antikoerper, Gjb-3 antikoerper, ekv antikoerper, cx31 antikoerper, dfna2 antikoerper, gjb3b antikoerper, dfna2b antikoerper, connexin-31 antikoerper, gap junction protein beta 3 antikoerper, gap junction protein, beta 3 antikoerper, gap junction protein beta 3 L homeolog antikoerper, GJB3 antikoerper, Gjb3 antikoerper, gjb3.L antikoerper, gjb3 antikoerper

Hintergrund: Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. Defects in GJB3 have been linked to erythrokeratodermia variabilis (EKV) is an autosomal dominant genodermatosis characterized by transient figurate red patches or hyperkeratosis. Mutations in GJB2 have also been associated with genetically derived hearing impairments, including autosomal recessive nonsyndromic deafness.

Molekulargewicht: 31 kDa

Gen-ID: 2707

UniProt: O75712

Pathways: Sensory Perception of Sound