TMPRSS12 Antikörper (N-Term)

Produktnummer ABIN5535821

Produktdetails anti-TMPRSS12 Antikörper

Target: TMPRSS12 (Transmembrane (C-terminal) Protease, serine 12 (TMPRSS12))

Bindungsspezifität: AA 26-54, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMPRSS12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TMPRSS12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-54 amino acids from the N-terminal region of human TMPRSS12.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu TMPRSS12

Target: TMPRSS12 (Transmembrane (C-terminal) Protease, serine 12 (TMPRSS12))

Andere Bezeichnung: TMPRSS12 (TMPRSS12 Produkte)

Synonyme: 4930478A21Rik antikoerper, transmembrane protease, serine 12 antikoerper, transmembrane (C-terminal) protease, serine 12 antikoerper, TMPRSS12 antikoerper, tmprss12 antikoerper, Tmprss12 antikoerper

Hintergrund: TMPRSS12 (transmembrane protease serine 12) is a 348 amino acid single-pass membrane protein that belong to the peptidase S1 family and contains one peptidase S1 domain. The gene that encodes TMPRSS12 consists of nearly 45,000 bases and maps to human chromosome 12q13.12. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster, which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster, encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms which vary in severity depending on the extent of mosaicism.

Molekulargewicht: 39 kDa

Gen-ID: 283471

UniProt: Q86WS5