CHRNA2 Antikörper (N-Term)

Produktnummer ABIN5535638

Produktdetails anti-CHRNA2 Antikörper

Target: CHRNA2 (Cholinergic Receptor, Nicotinic, alpha 2 (Neuronal) (CHRNA2))

Bindungsspezifität: AA 42-69, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHRNA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CHRNA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-69 amino acids from the N-terminal region of human CHRNA2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu CHRNA2

Target: CHRNA2 (Cholinergic Receptor, Nicotinic, alpha 2 (Neuronal) (CHRNA2))

Andere Bezeichnung: CHRNA2 (CHRNA2 Produkte)

Synonyme: CHRNA2 antikoerper, NACHRA2 antikoerper, chrna2 antikoerper, zgc:136717 antikoerper, ACHR antikoerper, Acra-2 antikoerper, Acra2 antikoerper, BC011490 antikoerper, cholinergic receptor nicotinic alpha 2 subunit antikoerper, cholinergic receptor, nicotinic, alpha 2a (neuronal) antikoerper, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal) antikoerper, neuronal acetylcholine receptor subunit alpha-2 antikoerper, neuronal acetylcholine receptor subunit alpha-4-like antikoerper, CHRNA2 antikoerper, chrna2a antikoerper, Chrna2 antikoerper, CpipJ_CPIJ002436 antikoerper, LOC100370261 antikoerper, Tsp_10995 antikoerper

Hintergrund: Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission. This gene encodes an alpha subunit that is widely expressed in the brain. The proposed structure for nAChR subunits is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4. Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence.

Molekulargewicht: 60 kDa

Gen-ID: 1135

UniProt: Q15822