PPIL5 Antikörper (AA 127-153)

Produktnummer ABIN5535141

Produktdetails anti-PPIL5 Antikörper

Target: PPIL5 (LRR1) (Leucine Rich Repeat Protein 1 (LRR1))

Bindungsspezifität: AA 127-153

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPIL5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PPIL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-153 amino acids from the Central region of human PPIL5.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.48 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PPIL5

Target: PPIL5 (LRR1) (Leucine Rich Repeat Protein 1 (LRR1))

Andere Bezeichnung: PPIL5 (LRR1 Produkte)

Synonyme: 2410005L11Rik antikoerper, AU021780 antikoerper, LRR-1 antikoerper, Ppil5 antikoerper, 4-1BBLRR antikoerper, PPIL5 antikoerper, leucine rich repeat protein 1 antikoerper, Lrr1 antikoerper, LRR1 antikoerper

Hintergrund: The protein encoded by this gene contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2), which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed.

Molekulargewicht: 47 kDa

Gen-ID: 122769

UniProt: Q96L50