USP22 Antikörper (C-Term)
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- Target Alle USP22 Antikörper anzeigen
- USP22 (Ubiquitin Specific Peptidase 22 (USP22))
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Bindungsspezifität
- AA 351-380, C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser USP22 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
- Immunogen
- This USP22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 351-380 amino acids from the C-terminal region of human USP22.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product USP22 Primärantikörper
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- Applikationshinweise
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For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.17 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- USP22 (Ubiquitin Specific Peptidase 22 (USP22))
- Andere Bezeichnung
- USP22 (USP22 Produkte)
- Synonyme
- USP3L antikoerper, AI427806 antikoerper, zgc:136342 antikoerper, usp22 antikoerper, usp22 b antikoerper, usp22-B antikoerper, usp22-a antikoerper, usp3l antikoerper, ubiquitin specific peptidase 22 antikoerper, ubiquitin specific peptidase 22 S homeolog antikoerper, USP22 antikoerper, Usp22 antikoerper, usp22 antikoerper, usp22.S antikoerper
- Hintergrund
- Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.
- Molekulargewicht
- 60 kDa
- Gen-ID
- 23326
- UniProt
- Q9UPT9
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