ZBTB7B Antikörper (C-Term)

Produktnummer ABIN5534847

Produktdetails anti-ZBTB7B Antikörper

Target: ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))

Bindungsspezifität: AA 440-469, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZBTB7B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This ZBTB7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 440-469 amino acids from the C-terminal region of human ZBTB7B.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IF starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu ZBTB7B

Target: ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))

Andere Bezeichnung: ZBTB7B (ZBTB7B Produkte)

Synonyme: THPOK antikoerper, ZBTB15 antikoerper, ZFP-67 antikoerper, ZFP67 antikoerper, ZNF857B antikoerper, c-KROX antikoerper, hcKROX antikoerper, Thpok antikoerper, Zfp67 antikoerper, c-Krox antikoerper, ZBTB7B antikoerper, zbtb7b antikoerper, MGC130914 antikoerper, zinc finger and BTB domain containing 7B antikoerper, kruppel-related zinc finger protein hcKrox antikoerper, ZBTB7B antikoerper, Zbtb7b antikoerper, zbtb7b antikoerper

Hintergrund: ZBTB7B is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes. It may also function as a repressor of fibronectin and possibly other extracellular matrix genes.

Molekulargewicht: 58 kDa

Gen-ID: 51043

UniProt: O15156