NDST1 Antikörper (C-Term)

Produktnummer ABIN5534558

Produktdetails anti-NDST1 Antikörper

Target: NDST1 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 1 (NDST1))

Bindungsspezifität: AA 820-849, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NDST1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NDST1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 820-849 amino acids from the C-terminal region of human NDST1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu NDST1

Target: NDST1 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 1 (NDST1))

Andere Bezeichnung: NDST1 (NDST1 Produkte)

Synonyme: HSST antikoerper, NST1 antikoerper, 1200015G06Rik antikoerper, Hsst antikoerper, NDST-1 antikoerper, fj47c03 antikoerper, ndst1 antikoerper, wu:fj47c03 antikoerper, NDST1 antikoerper, N-deacetylase and N-sulfotransferase 1 antikoerper, N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 antikoerper, N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1b antikoerper, N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 S homeolog antikoerper, NDST1 antikoerper, Ndst1 antikoerper, ndst1b antikoerper, ndst1 antikoerper, ndst1.S antikoerper

Hintergrund: NDST1 is an essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA dissacharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L-selectin ligands, thereby playing a role in inflammatory response.

Molekulargewicht: 101 kDa

Gen-ID: 3340

UniProt: P52848

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Glycosaminoglycan Metabolic Process